Sağlık Bi̇li̇mleri̇
Kanser Tedavi̇leri̇ Yan Etki̇ Yöneti̇mi̇
Yayınevi:
Cumhuriyet Üniversitesi Yayınları
Kanser, günümüzde ne yazık ki hala insan hayatını tehdit eden, gittikçe yaygınlığı artan, hem hasta hem hasta yakınlarının yaşamına etkileri olan, mortalite ve morbidite bakımından tüm dünyadaki önemli hastalıkların başında gelmektedir. Yaygınlığının bu kadar artmasına rağmen kanser tedavileri için de çok yaygın araştırmalar yapılmakta ve etkinliği bilinen çok sayıda kemoterapi ve radyoterapi uygulamalarının yanı sıra yeni nesil hedefe yönelik ilaçların bulunması da kanser tedavisinin gücünü artırmada büyük umutlar vadetmektedir.
Kanser tedavileri çoğu zaman yan etkilerinin fazlaca olduğu, hekimler için hem kanseri tedavi ederken hem de bu yan etkilerle de baş etmeyi gerektiren uzun bir süreci kapsar. Özellikle Tıp Eğitimi ve Tıpta Uzmanlık Eğitimleri sırasında kanser tedavilerine karşı gelişen yan etkilerin ve bunların yönetiminin öğretilmesi, hekimlik meslekleri sırasında da büyük destek sağlamaktadır. Bu amaçla, hazırlanmış olan bu kitabın kanser hastasına yaklaşımda önemli katkıları olacağını düşünmekteyiz.
Başta bu kitabın hazırlanmasında emeği geçen hocalarım olmak üzere, kanserle mücadeleye destek veren tüm bilim insanlarına ayrıca kitabımızın basılmasında desteklerini esirgemeyen Sivas Cumhuriyet Üniversitesi Rektörü Prof. Dr. Alim YILDIZ’a teşekkür ediyoruz.
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Burak TÜZÜN, Hilmi ATASEVEN, Prof Dr. Koray SAYIN
Hilmi ATASEVEN, Zekiye HASBEK
/* Action Buttons */
.action-buttons {
display: flex;
flex-direction: column;
gap: 1rem;
}
.modern-action-btn {
background: linear-gradient(135deg, #dc3545 0%, #c82333 100%);
color: white;
padding: 1rem 2rem;
border-radius: 12px;
text-decoration: none;
font-weight: 600;
font-size: 1rem;
text-align: center;
border: none;
transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
box-shadow: 0 4px 16px rgba(220, 53, 69, 0.2);
display: flex;
align-items: center;
justify-content: center;
gap: 0.75rem;
}
.modern-action-btn.secondary-btn {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
box-shadow: 0 4px 16px rgba(108, 117, 125, 0.2);
}
.modern-action-btn:hover {
transform: translateY(-2px);
box-shadow: 0 8px 24px rgba(220, 53, 69, 0.3);
color: white;
text-decoration: none;
}
.modern-action-btn.secondary-btn:hover {
box-shadow: 0 8px 24px rgba(108, 117, 125, 0.3);
}
.auth-buttons {
display: grid;
grid-template-columns: 1fr 1fr;
gap: 1rem;
}
.auth-notice .notice-card {
background: linear-gradient(135deg, #17a2b8 0%, #138496 100%);
color: white;
padding: 1rem 1.5rem;
border-radius: 12px;
display: flex;
align-items: center;
gap: 0.75rem;
font-weight: 500;
box-shadow: 0 4px 16px rgba(23, 162, 184, 0.2);
}
.notice-icon {
font-size: 1.25rem;
flex-shrink: 0;
}
/* Info Cards */
.info-card {
background: white;
border-radius: 16px;
box-shadow: 0 4px 16px rgba(0, 0, 0, 0.08);
border: 1px solid #e9ecef;
overflow: hidden;
transition: all 0.3s ease;
}
.info-card:hover {
transform: translateY(-2px);
box-shadow: 0 8px 24px rgba(0, 0, 0, 0.12);
}
.info-card .card-header {
background: linear-gradient(135deg, #dc3545 0%, #c82333 100%);
color: white;
padding: 1.25rem 1.5rem;
border-bottom: none;
}
/* Combined Content Styling */
.combined-content {
display: flex;
gap: 2rem;
align-items: flex-start;
}
.info-section {
flex: 0 0 40%;
min-width: 300px;
}
.description-section {
flex: 1;
background: #f8f9fa;
border-radius: 12px;
padding: 1.5rem;
border: 1px solid #e9ecef;
}
.description-title {
color: #2c3e50;
font-weight: 600;
font-size: 1rem;
margin-bottom: 1rem;
display: flex;
align-items: center;
}
.info-grid-compact {
display: grid;
grid-template-columns: 1fr;
gap: 1rem;
}
.card-title {
margin: 0;
font-weight: 600;
font-size: 1.1rem;
display: flex;
align-items: center;
gap: 0.75rem;
}
.card-icon {
font-size: 1.25rem;
opacity: 0.9;
}
.card-content {
padding: 1.5rem;
}
.info-grid {
display: grid;
grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
gap: 1.5rem;
}
.info-item {
display: flex;
flex-direction: column;
gap: 0.5rem;
}
.info-label {
font-weight: 600;
color: #2c3e50;
font-size: 0.9rem;
text-transform: uppercase;
letter-spacing: 0.5px;
}
.info-value {
color: #6c757d;
font-size: 1rem;
}
.type-badge {
padding: 0.375rem 0.75rem;
border-radius: 20px;
font-weight: 600;
font-size: 0.8rem;
text-transform: uppercase;
letter-spacing: 0.5px;
}
.type-dijital {
background: linear-gradient(135deg, #17a2b8 0%, #138496 100%);
color: white;
}
.type-ikisi {
background: linear-gradient(135deg, #28a745 0%, #20c997 100%);
color: white;
}
.type-fiziksel {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
color: white;
}
/* Description */
.description-text {
font-size: 1rem;
line-height: 1.8;
color: #495057;
text-align: justify;
}
/* Social Share */
.social-share {
text-align: center;
background: #f8f9fa;
border-radius: 16px;
padding: 1.5rem;
border: 1px solid #e9ecef;
}
.share-title {
color: #2c3e50;
font-weight: 600;
margin-bottom: 1.5rem;
font-size: 1.1rem;
}
.share-buttons {
display: flex;
justify-content: center;
gap: 0.75rem;
flex-wrap: wrap;
}
.share-btn {
padding: 0.75rem 1rem;
border-radius: 50px;
text-decoration: none;
font-weight: 600;
font-size: 0.9rem;
transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
display: flex;
align-items: center;
gap: 0.5rem;
border: 2px solid transparent;
position: relative;
overflow: hidden;
}
.share-btn.facebook {
background: linear-gradient(135deg, #3b5998 0%, #2d4373 100%);
color: white;
}
.share-btn.twitter {
background: linear-gradient(135deg, #1da1f2 0%, #0d8bd9 100%);
color: white;
}
.share-btn.whatsapp {
background: linear-gradient(135deg, #25d366 0%, #20ba5a 100%);
color: white;
}
.share-btn.email {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
color: white;
}
.share-btn:hover {
transform: translateY(-3px);
box-shadow: 0 6px 20px rgba(0, 0, 0, 0.15);
color: white;
text-decoration: none;
}
/* Related Products Section */
.related-products, .author-products {
background: linear-gradient(135deg, #f8f9fa 0%, #e9ecef 100%);
}
.section-header {
text-align: center;
}
.section-main-title {
color: #2c3e50;
font-weight: 700;
font-size: 2rem;
margin-bottom: 0.5rem;
display: flex;
align-items: center;
justify-content: center;
gap: 1rem;
}
.section-main-title .section-icon {
color: #dc3545;
font-size: 1.75rem;
}
/* Products Grid for Related */
.products-grid {
display: grid;
grid-template-columns: repeat(auto-fill, minmax(280px, 1fr));
gap: 2rem;
padding: 0;
}
.products-grid .product-card {
background: white;
border-radius: 16px;
overflow: hidden;
box-shadow: 0 4px 16px rgba(0, 0, 0, 0.08);
border: 1px solid #e9ecef;
transition: all 0.4s cubic-bezier(0.4, 0, 0.2, 1);
}
.products-grid .product-card:hover {
transform: translateY(-6px) scale(1.02);
box-shadow: 0 12px 32px rgba(0, 0, 0, 0.15);
}
.products-grid .product-image {
height: 260px;
overflow: hidden;
background: #f8f9fa;
position: relative;
}
.products-grid .product-image-actions {
position: absolute;
top: 12px;
right: 12px;
z-index: 5;
opacity: 1;
}
.products-grid .btn-view-detail {
display: inline-flex;
align-items: center;
justify-content: center;
width: 40px;
height: 40px;
background: rgba(0, 0, 0, 0.6);
border: none;
border-radius: 50%;
font-size: 1rem;
color: white;
text-decoration: none;
transition: all 0.3s ease;
}
.products-grid .btn-view-detail:hover {
transform: scale(1.1);
background: rgba(220, 53, 69, 0.9);
color: white;
}
.products-grid .product-image img {
width: 100%;
height: 100%;
object-fit: contain;
padding: 1rem;
transition: transform 0.3s ease;
}
.products-grid .product-info {
padding: 1.25rem;
}
.products-grid .product-title {
margin-bottom: 0.75rem;
}
.products-grid .product-title a {
color: #2c3e50;
text-decoration: none;
font-weight: 600;
font-size: 1rem;
line-height: 1.4;
transition: color 0.3s ease;
}
.products-grid .product-title a:hover {
color: #dc3545;
text-decoration: none;
}
.products-grid .product-author {
color: #6c757d;
font-size: 0.9rem;
margin-bottom: 1rem;
font-style: italic;
}
.products-grid .stock-status {
background: #d4841a;
color: white;
border-radius: 8px;
padding: 0.75rem 1rem;
display: flex;
align-items: center;
justify-content: space-between;
margin-top: auto;
}
.products-grid .stock-status.out-of-stock {
background: #6c757d;
}
.products-grid .stock-text {
font-weight: 700;
font-size: 0.8rem;
letter-spacing: 0.5px;
}
.products-grid .stock-status .price-info {
display: flex;
align-items: center;
gap: 0.5rem;
white-space: nowrap;
}
.products-grid .current-price {
font-weight: 700;
font-size: 1.1rem;
color: #ffffff;
}
.products-grid .btn-add-cart-inline {
background: #dc3545;
color: #ffffff;
border: none;
width: 42px;
height: 42px;
border-radius: 50%;
display: flex;
align-items: center;
justify-content: center;
font-size: 1.1rem;
transition: all 0.3s ease;
margin-left: 0.5rem;
}
.products-grid .btn-add-cart-inline:hover {
background: #b02a37;
color: #ffffff;
transform: scale(1.1);
}
.products-grid .empty-state-card {
background: white;
border-radius: 16px;
border: 1px solid #e9ecef;
padding: 2rem;
text-align: center;
color: #6c757d;
grid-column: 1 / -1;
}
.products-grid .empty-state-content {
display: flex;
flex-direction: column;
align-items: center;
gap: 0.75rem;
font-weight: 600;
}
.products-grid .empty-state-content i {
font-size: 2rem;
color: #dc3545;
}
/* Responsive Design */
@media (max-width: 768px) {
.product-detail-title {
font-size: 1.5rem;
}
.product-detail-subtitle {
font-size: 1rem;
}
.auth-buttons {
grid-template-columns: 1fr;
}
.info-grid {
grid-template-columns: 1fr;
}
.combined-content {
flex-direction: column;
gap: 1.5rem;
}
.info-section {
flex: none;
min-width: auto;
}
.share-buttons {
flex-direction: column;
align-items: center;
}
.share-btn {
width: 100%;
max-width: 200px;
justify-content: center;
}
.author-card {
flex-direction: column;
text-align: center;
}
.section-main-title {
font-size: 1.5rem;
}
.products-grid {
grid-template-columns: repeat(auto-fill, minmax(250px, 1fr));
gap: 1.5rem;
}
}
@media (max-width: 576px) {
.modern-stock-status {
flex-direction: column;
gap: 1rem;
text-align: center;
}
.current-price {
font-size: 1.75rem;
}
.products-grid {
grid-template-columns: 1fr;
gap: 1.5rem;
}
}
/* Loading and Animation States */
.product-card {
animation: fadeInUp 0.6s ease-out;
}
@keyframes fadeInUp {
from {
opacity: 0;
transform: translateY(30px);
}
to {
opacity: 1;
transform: translateY(0);
}
}
/* Legacy compatibility */
.hover-shadow {
transition: all 0.3s ease;
}
.hover-shadow:hover {
transform: translateY(-5px);
box-shadow: 0 10px 30px rgba(0,0,0,0.15) !important;
}
.main-image-container {
background: #f8f9fa;
padding: 20px;
border-radius: 10px;
}
.badge-lg {
padding: 8px 15px;
font-size: 14px;
}