Sağlık Bi̇li̇mleri̇
Küçük Hücreli Akciğer Kanserlerinde Güncel Tanı Ve Tedavi Yaklaşımları
Yayınevi:
Cumhuriyet Üniversitesi Yayınları
Küçük hücreli akciğer kanseri (KHAK), dünyada yaygın görülen kanser türlerinden biri olup, her yıl binlerce insanı etkilemektedir. Tanı ve tedavi süreçleri, tıp profesyonelleri için sürekli bir zorluk teşkil etmektedir.
KHAK’nın karmaşık yapısını anlamak, bu hastalığın erken tanı ve tedavi süreçlerinde büyük önem taşımaktadır. Kitap, bilimsel veriler ve araştırmalar ışığında okuyuculara güncel bilgiler sunmayı hedeflemektedir. Amacımız, tıp profesyonellerinin bilgi birikimlerini artırarak, hastalar için daha etkili ve insan odaklı tanı ve tedavi yöntemleri geliştirmelerine yardımcı olmaktır.
Umuyoruz ki, bu kitap, tıp öğrencileri, asistanlar, uzmanlar ve akademisyenler için KHAK hakkında kapsamlı bir bilgi kaynağı olur ve hastalığın tanı, tedavi ve yönetiminde derinlemesine bir bilgi ve anlayış sağlar.
Başta bu kitabın hazırlanmasında emeği geçen hocalarımız olmak üzere, Kanser Çalışmaları Uygulama ve Araştırma Merkezine (KANAM), kanserle mücadele eden tüm bilim insanlarına, mücadeleye destek olan tüm sağlık çalışanlarına ve kitabın basımını gerçekleştiren üniversitemiz matbaa çalışanlarına yürekten teşekkür ediyoruz.
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Burak TÜZÜN, Hilmi ATASEVEN, Prof Dr. Koray SAYIN
Hilmi ATASEVEN, Zekiye HASBEK
/* Action Buttons */
.action-buttons {
display: flex;
flex-direction: column;
gap: 1rem;
}
.modern-action-btn {
background: linear-gradient(135deg, #dc3545 0%, #c82333 100%);
color: white;
padding: 1rem 2rem;
border-radius: 12px;
text-decoration: none;
font-weight: 600;
font-size: 1rem;
text-align: center;
border: none;
transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
box-shadow: 0 4px 16px rgba(220, 53, 69, 0.2);
display: flex;
align-items: center;
justify-content: center;
gap: 0.75rem;
}
.modern-action-btn.secondary-btn {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
box-shadow: 0 4px 16px rgba(108, 117, 125, 0.2);
}
.modern-action-btn:hover {
transform: translateY(-2px);
box-shadow: 0 8px 24px rgba(220, 53, 69, 0.3);
color: white;
text-decoration: none;
}
.modern-action-btn.secondary-btn:hover {
box-shadow: 0 8px 24px rgba(108, 117, 125, 0.3);
}
.auth-buttons {
display: grid;
grid-template-columns: 1fr 1fr;
gap: 1rem;
}
.auth-notice .notice-card {
background: linear-gradient(135deg, #17a2b8 0%, #138496 100%);
color: white;
padding: 1rem 1.5rem;
border-radius: 12px;
display: flex;
align-items: center;
gap: 0.75rem;
font-weight: 500;
box-shadow: 0 4px 16px rgba(23, 162, 184, 0.2);
}
.notice-icon {
font-size: 1.25rem;
flex-shrink: 0;
}
/* Info Cards */
.info-card {
background: white;
border-radius: 16px;
box-shadow: 0 4px 16px rgba(0, 0, 0, 0.08);
border: 1px solid #e9ecef;
overflow: hidden;
transition: all 0.3s ease;
}
.info-card:hover {
transform: translateY(-2px);
box-shadow: 0 8px 24px rgba(0, 0, 0, 0.12);
}
.info-card .card-header {
background: linear-gradient(135deg, #dc3545 0%, #c82333 100%);
color: white;
padding: 1.25rem 1.5rem;
border-bottom: none;
}
/* Combined Content Styling */
.combined-content {
display: flex;
gap: 2rem;
align-items: flex-start;
}
.info-section {
flex: 0 0 40%;
min-width: 300px;
}
.description-section {
flex: 1;
background: #f8f9fa;
border-radius: 12px;
padding: 1.5rem;
border: 1px solid #e9ecef;
}
.description-title {
color: #2c3e50;
font-weight: 600;
font-size: 1rem;
margin-bottom: 1rem;
display: flex;
align-items: center;
}
.info-grid-compact {
display: grid;
grid-template-columns: 1fr;
gap: 1rem;
}
.card-title {
margin: 0;
font-weight: 600;
font-size: 1.1rem;
display: flex;
align-items: center;
gap: 0.75rem;
}
.card-icon {
font-size: 1.25rem;
opacity: 0.9;
}
.card-content {
padding: 1.5rem;
}
.info-grid {
display: grid;
grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
gap: 1.5rem;
}
.info-item {
display: flex;
flex-direction: column;
gap: 0.5rem;
}
.info-label {
font-weight: 600;
color: #2c3e50;
font-size: 0.9rem;
text-transform: uppercase;
letter-spacing: 0.5px;
}
.info-value {
color: #6c757d;
font-size: 1rem;
}
.type-badge {
padding: 0.375rem 0.75rem;
border-radius: 20px;
font-weight: 600;
font-size: 0.8rem;
text-transform: uppercase;
letter-spacing: 0.5px;
}
.type-dijital {
background: linear-gradient(135deg, #17a2b8 0%, #138496 100%);
color: white;
}
.type-ikisi {
background: linear-gradient(135deg, #28a745 0%, #20c997 100%);
color: white;
}
.type-fiziksel {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
color: white;
}
/* Description */
.description-text {
font-size: 1rem;
line-height: 1.8;
color: #495057;
text-align: justify;
}
/* Social Share */
.social-share {
text-align: center;
background: #f8f9fa;
border-radius: 16px;
padding: 1.5rem;
border: 1px solid #e9ecef;
}
.share-title {
color: #2c3e50;
font-weight: 600;
margin-bottom: 1.5rem;
font-size: 1.1rem;
}
.share-buttons {
display: flex;
justify-content: center;
gap: 0.75rem;
flex-wrap: wrap;
}
.share-btn {
padding: 0.75rem 1rem;
border-radius: 50px;
text-decoration: none;
font-weight: 600;
font-size: 0.9rem;
transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
display: flex;
align-items: center;
gap: 0.5rem;
border: 2px solid transparent;
position: relative;
overflow: hidden;
}
.share-btn.facebook {
background: linear-gradient(135deg, #3b5998 0%, #2d4373 100%);
color: white;
}
.share-btn.twitter {
background: linear-gradient(135deg, #1da1f2 0%, #0d8bd9 100%);
color: white;
}
.share-btn.whatsapp {
background: linear-gradient(135deg, #25d366 0%, #20ba5a 100%);
color: white;
}
.share-btn.email {
background: linear-gradient(135deg, #6c757d 0%, #5a6268 100%);
color: white;
}
.share-btn:hover {
transform: translateY(-3px);
box-shadow: 0 6px 20px rgba(0, 0, 0, 0.15);
color: white;
text-decoration: none;
}
/* Related Products Section */
.related-products, .author-products {
background: linear-gradient(135deg, #f8f9fa 0%, #e9ecef 100%);
}
.section-header {
text-align: center;
}
.section-main-title {
color: #2c3e50;
font-weight: 700;
font-size: 2rem;
margin-bottom: 0.5rem;
display: flex;
align-items: center;
justify-content: center;
gap: 1rem;
}
.section-main-title .section-icon {
color: #dc3545;
font-size: 1.75rem;
}
/* Products Grid for Related */
.products-grid {
display: grid;
grid-template-columns: repeat(auto-fill, minmax(280px, 1fr));
gap: 2rem;
padding: 0;
}
.products-grid .product-card {
background: white;
border-radius: 16px;
overflow: hidden;
box-shadow: 0 4px 16px rgba(0, 0, 0, 0.08);
border: 1px solid #e9ecef;
transition: all 0.4s cubic-bezier(0.4, 0, 0.2, 1);
}
.products-grid .product-card:hover {
transform: translateY(-6px) scale(1.02);
box-shadow: 0 12px 32px rgba(0, 0, 0, 0.15);
}
.products-grid .product-image {
height: 260px;
overflow: hidden;
background: #f8f9fa;
position: relative;
}
.products-grid .product-image-actions {
position: absolute;
top: 12px;
right: 12px;
z-index: 5;
opacity: 1;
}
.products-grid .btn-view-detail {
display: inline-flex;
align-items: center;
justify-content: center;
width: 40px;
height: 40px;
background: rgba(0, 0, 0, 0.6);
border: none;
border-radius: 50%;
font-size: 1rem;
color: white;
text-decoration: none;
transition: all 0.3s ease;
}
.products-grid .btn-view-detail:hover {
transform: scale(1.1);
background: rgba(220, 53, 69, 0.9);
color: white;
}
.products-grid .product-image img {
width: 100%;
height: 100%;
object-fit: contain;
padding: 1rem;
transition: transform 0.3s ease;
}
.products-grid .product-info {
padding: 1.25rem;
}
.products-grid .product-title {
margin-bottom: 0.75rem;
}
.products-grid .product-title a {
color: #2c3e50;
text-decoration: none;
font-weight: 600;
font-size: 1rem;
line-height: 1.4;
transition: color 0.3s ease;
}
.products-grid .product-title a:hover {
color: #dc3545;
text-decoration: none;
}
.products-grid .product-author {
color: #6c757d;
font-size: 0.9rem;
margin-bottom: 1rem;
font-style: italic;
}
.products-grid .stock-status {
background: #d4841a;
color: white;
border-radius: 8px;
padding: 0.75rem 1rem;
display: flex;
align-items: center;
justify-content: space-between;
margin-top: auto;
}
.products-grid .stock-status.out-of-stock {
background: #6c757d;
}
.products-grid .stock-text {
font-weight: 700;
font-size: 0.8rem;
letter-spacing: 0.5px;
}
.products-grid .stock-status .price-info {
display: flex;
align-items: center;
gap: 0.5rem;
white-space: nowrap;
}
.products-grid .current-price {
font-weight: 700;
font-size: 1.1rem;
color: #ffffff;
}
.products-grid .btn-add-cart-inline {
background: #dc3545;
color: #ffffff;
border: none;
width: 42px;
height: 42px;
border-radius: 50%;
display: flex;
align-items: center;
justify-content: center;
font-size: 1.1rem;
transition: all 0.3s ease;
margin-left: 0.5rem;
}
.products-grid .btn-add-cart-inline:hover {
background: #b02a37;
color: #ffffff;
transform: scale(1.1);
}
.products-grid .empty-state-card {
background: white;
border-radius: 16px;
border: 1px solid #e9ecef;
padding: 2rem;
text-align: center;
color: #6c757d;
grid-column: 1 / -1;
}
.products-grid .empty-state-content {
display: flex;
flex-direction: column;
align-items: center;
gap: 0.75rem;
font-weight: 600;
}
.products-grid .empty-state-content i {
font-size: 2rem;
color: #dc3545;
}
/* Responsive Design */
@media (max-width: 768px) {
.product-detail-title {
font-size: 1.5rem;
}
.product-detail-subtitle {
font-size: 1rem;
}
.auth-buttons {
grid-template-columns: 1fr;
}
.info-grid {
grid-template-columns: 1fr;
}
.combined-content {
flex-direction: column;
gap: 1.5rem;
}
.info-section {
flex: none;
min-width: auto;
}
.share-buttons {
flex-direction: column;
align-items: center;
}
.share-btn {
width: 100%;
max-width: 200px;
justify-content: center;
}
.author-card {
flex-direction: column;
text-align: center;
}
.section-main-title {
font-size: 1.5rem;
}
.products-grid {
grid-template-columns: repeat(auto-fill, minmax(250px, 1fr));
gap: 1.5rem;
}
}
@media (max-width: 576px) {
.modern-stock-status {
flex-direction: column;
gap: 1rem;
text-align: center;
}
.current-price {
font-size: 1.75rem;
}
.products-grid {
grid-template-columns: 1fr;
gap: 1.5rem;
}
}
/* Loading and Animation States */
.product-card {
animation: fadeInUp 0.6s ease-out;
}
@keyframes fadeInUp {
from {
opacity: 0;
transform: translateY(30px);
}
to {
opacity: 1;
transform: translateY(0);
}
}
/* Legacy compatibility */
.hover-shadow {
transition: all 0.3s ease;
}
.hover-shadow:hover {
transform: translateY(-5px);
box-shadow: 0 10px 30px rgba(0,0,0,0.15) !important;
}
.main-image-container {
background: #f8f9fa;
padding: 20px;
border-radius: 10px;
}
.badge-lg {
padding: 8px 15px;
font-size: 14px;
}